BDBM50340678 1-(beta-D-2-deoxy-erythro-pentofuranosyl)-5-fluorouracil::2'-deoxy-5-fluorouridine::5-Fluoro-1-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione::5-Fluoro-1-(4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione::5-fluoro-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione::5-fluoro-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione::5-fluoro-2'-Deoxy-uridine::5-fluoro-2'-deoxyuridine::CHEMBL917::FLOXURIDINE::FUDR::Fluoruridine Deoxyribose
SMILES OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
InChI Key InChIKey=ODKNJVUHOIMIIZ-RRKCRQDMSA-N
Data 16 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 50340678
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human CNT2 expressed in COS7 cells assessed as reduction in sodium-dependent [14C]-inosine uptake in presence of Na+ by liquid scintill...More data for this Ligand-Target Pair
TargetSolute carrier family 15 member 1(Homo sapiens (Human))
Jiangxi University Of Traditional Chinese Medicine
Curated by ChEMBL
Jiangxi University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 1.22E+7nMAssay Description:Substrate activity at PEPT1 (unknown origin) expressed in MDCK cells assessed as inhibition of gly-sar uptake incubated for 10 mins by HPLC/MS/MS ana...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 4 h...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 24 ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 15...More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 4 ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 24...More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibition of cellular thymidylate synthase activity of murine leukemia cell line (L1210) in intact cells.More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of cellular thymidylate synthase activity of mouse fibroblast (L929 TK-) in permeabilised cells.More data for this Ligand-Target Pair
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition of cellular thymidylate synthase activity of murine leukemia cell line (L1210) in permeabilised cells.More data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of cellular thymidylate synthase activity of mouse fibroblast (L929 TK-) in intact cells.More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Thymidylate synthase inhibition in thymidine kinase deficient /TK cells after 2 h treatmentMore data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Thymidylate synthase inhibition in wild type LM cells after 2 h treatmentMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40E+3nMAssay Description:Thymidylate synthase inhibition in thymidine kinase deficient LM cells after 2 h treatmentMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Thymidylate synthase inhibition in L1210 mouse leukemia cells after 2 h treatmentMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 15 ...More data for this Ligand-Target Pair