BDBM50340730 5,7-Dimethyl-2-(ethylthio)-3-phenylsulfonyl-pyrazolo[1,5-a]pyrimidine::CHEMBL1762568::US8552005, 1.1(6)

SMILES CCSc1nn2c(C)cc(C)nc2c1S(=O)(=O)c1ccccc1

InChI Key InChIKey=YJUVKKHOHPQYMO-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50340730   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50340730(5,7-Dimethyl-2-(ethylthio)-3-phenylsulfonyl-pyrazo...)
Affinity DataKi:  1.91nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP production after 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50340730(5,7-Dimethyl-2-(ethylthio)-3-phenylsulfonyl-pyrazo...)
Affinity DataIC50:  50nMAssay Description:Functional assay using 5-HT6 receptors.More data for this Ligand-Target Pair
In DepthDetails US Patent