BDBM50340908 (4-amino-2-(pyridin-3-ylamino)thiazol-5-yl)(3-methoxyphenyl)methanone::CHEMBL1761797
SMILES COc1cccc(c1)C(=O)c1sc(Nc2cccnc2)nc1N
InChI Key InChIKey=IVPOEQUCSQIXKZ-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50340908
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of CDK5/p25 assessed as [33P]gamma-ATP incorporation into peptide PKTPKKAKKL substrate after 45 mins by scintillation counterMore data for this Ligand-Target Pair