BDBM50341060 3-(1-(1,3,5-triazin-2-yl)-1H-benzo[d]imidazol-2-ylamino)phenol::CHEMBL1762779
SMILES Oc1cccc(Nc2nc3ccccc3n2-c2ncncn2)c1
InChI Key InChIKey=QTRNQOMQZCJUIY-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50341060
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of mTOR in human U-87 cells assessed as inhibition of phosphorylation of AKT at S473More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of mTOR assessed as inhibition of phosphorylation of 4EBP1 by Lantha-Screen enzyme assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of mTOR in human U-87 cells assessed as inhibition of phosphorylation of 4EBP1 at T37/46More data for this Ligand-Target Pair
