BDBM50341197 CHEMBL1760891::cis-N-(7-(N-ethylacetamido)-4-methoxybenzo[d]thiazol-2-yl)-3-(3-(trifluoromethyl)benzylamino)cyclopentanecarboxamide 2,2,2-trifluoroacetate

SMILES CCN(C(C)=O)c1ccc(OC)c2nc(NC(=O)[C@@H]3CC[C@@H](C3)NCc3cccc(c3)C(F)(F)F)sc12

InChI Key InChIKey=WOGFEHLAXZBDOW-MJGOQNOKSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50341197   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50341197(CHEMBL1760891 | cis-N-(7-(N-ethylacetamido)-4-meth...)
Affinity DataKi:  180nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50341197(CHEMBL1760891 | cis-N-(7-(N-ethylacetamido)-4-meth...)
Affinity DataKi:  220nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A1 receptor after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50341197(CHEMBL1760891 | cis-N-(7-(N-ethylacetamido)-4-meth...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human adenosine A2B receptor expressed in CHO cells assessed as decrease in cellular cAMP level after 20 to 25 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed