BDBM50341228 1-(4-fluoro-2-(trifluoromethyl)phenyl)-9-(1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-2(1H)-one::CHEMBL1765714

SMILES: Fc1ccc(c(c1)C(F)(F)F)-n1c2c(ccc1=O)cnc1ccc(cc21)-c1cn[nH]c1

InChI Key: InChIKey=GDVQGEPAYBCRBS-UHFFFAOYSA-N

Data: 1 KI  1 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50341228   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Human)	BDBM50341228 (1-(4-fluoro-2-(trifluoromethyl)phenyl)-9-(1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	532	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Mouse)	BDBM50341228 (1-(4-fluoro-2-(trifluoromethyl)phenyl)-9-(1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	35	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM50341228 (1-(4-fluoro-2-(trifluoromethyl)phenyl)-9-(1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Human)	BDBM50341228 (1-(4-fluoro-2-(trifluoromethyl)phenyl)-9-(1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		252	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair