BDBM50341248 1,1-Dimethylethyl{(3R,5R)-1-[2-amino-6-(3-amino-1H-indazol-6-yl)-4-pyrimidinyl]-5-methyl-3-piperidinyl}carbamate::CHEMBL1614777::tert-butyl {(3R,5R)-1-[2-amino-6-(3-amino-2H-indazol-6-yl)pyrimidin-4-yl]-5-methylpiperidin-3-yl}carbamate

SMILES: C[C@@H]1C[C@H](CN(C1)c1cc(nc(N)n1)-c1ccc2c(N)[nH]nc2c1)NC(=O)OC(C)(C)C

InChI Key: InChIKey=YEIVLMDWYXFKHN-UHFFFAOYSA-N

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50341248   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3-phosphoinositide-dependent protein kinase 1 (Human)	BDBM50341248 (1,1-Dimethylethyl{(3R,5R)-1-[2-amino-6-(3-amino-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	151	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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3-phosphoinositide-dependent protein kinase 1 (Human)	BDBM50341248 (1,1-Dimethylethyl{(3R,5R)-1-[2-amino-6-(3-amino-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
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TGF-beta receptor type-1 (Human)	BDBM50341248 (1,1-Dimethylethyl{(3R,5R)-1-[2-amino-6-(3-amino-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Rho-associated protein kinase 1 (Human)	BDBM50341248 (1,1-Dimethylethyl{(3R,5R)-1-[2-amino-6-(3-amino-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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3-phosphoinositide-dependent protein kinase 1 (Human)	BDBM50341248 (1,1-Dimethylethyl{(3R,5R)-1-[2-amino-6-(3-amino-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50341248 (1,1-Dimethylethyl{(3R,5R)-1-[2-amino-6-(3-amino-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM50341248 (1,1-Dimethylethyl{(3R,5R)-1-[2-amino-6-(3-amino-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair