BDBM50341342 6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8H)-one::CHEMBL1230122

SMILES: CN1c2c(cnc(n2)NC3CCOCC3)C=C(C1=O)Oc4ccc(cc4F)F

InChI Key: InChIKey=KKKRKRMVJRHDMG-UHFFFAOYSA-N

Data: 6 IC50  13 Kd

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50341342   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase I isoform epsilon (Human)	BDBM50341342 (6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase 36 (Human)	BDBM50341342 (6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a
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Ribosomal protein S6 kinase alpha-4 (Human)	BDBM50341342 (6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a
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Ribosomal protein S6 kinase alpha-3 (Human)	BDBM50341342 (6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase NLK (Human)	BDBM50341342 (6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 10 (Human)	BDBM50341342 (6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 9 (Human)	BDBM50341342 (6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 8 (Human)	BDBM50341342 (6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a
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Cyclin-G-associated kinase (Human)	BDBM50341342 (6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a
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Epithelial discoidin domain-containing receptor 1 (Human)	BDBM50341342 (6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM50341342 (6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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Atypical kinase COQ8A, mitochondrial (Human)	BDBM50341342 (6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 11 (Human)	BDBM50341342 (6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM50341342 (6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50341342 (6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50341342 (6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50341342 (6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50341342 (6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50341342 (6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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