BDBM50341346 (R)-6-(2,4-difluorophenoxy)-8-methyl-2-(1-(methylsulfonyl)propan-2-ylamino)pyrido[2,3-d]pyrimidin-7(8H)-one::6-(2,4-Difluorophenoxy)-2-((R)-2-methanesulfonyl-1-methyl-ethylamino)-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one::6-(2,4-difluorophenoxy)-8-methyl-2-{[(1R)-1-methyl-2-(methylsulfonyl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one::CHEMBL1232769

SMILES: C[C@H](CS(=O)(=O)C)Nc1ncc2c(n1)N(C(=O)C(=C2)Oc3ccc(cc3F)F)C

InChI Key: InChIKey=DVEYHFXOGUYFBU-UHFFFAOYSA-N

Data: 1 IC50  5 Kd

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50341346   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Human)	BDBM50341346 ((R)-6-(2,4-difluorophenoxy)-8-methyl-2-(1-(methyls...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 8 (Human)	BDBM50341346 ((R)-6-(2,4-difluorophenoxy)-8-methyl-2-(1-(methyls...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 9 (Human)	BDBM50341346 ((R)-6-(2,4-difluorophenoxy)-8-methyl-2-(1-(methyls...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 10 (Human)	BDBM50341346 ((R)-6-(2,4-difluorophenoxy)-8-methyl-2-(1-(methyls...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM50341346 ((R)-6-(2,4-difluorophenoxy)-8-methyl-2-(1-(methyls...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 11 (Human)	BDBM50341346 ((R)-6-(2,4-difluorophenoxy)-8-methyl-2-(1-(methyls...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	8.70	n/a	n/a	n/a	n/a	n/a
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