BDBM50341411 CHEMBL4170435::US11534443, Example 43

SMILES COc1ncc(cc1NS(C)(=O)=O)-c1cc(OC2CCOCC2)c2nc(NC(C)=O)nc(C)c2c1

InChI Key InChIKey=RPKDUGMYXORHGJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50341411   

TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM50341411(CHEMBL4170435 | US11534443, Example 43)
Affinity DataIC50: 10nMAssay Description:The Kinase-Glo Kinase Assay Kit was purchased from Promega. All assays were performed at room temperature using white OptiPlate -384 well plate. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

LigandPNGBDBM50341411(CHEMBL4170435 | US11534443, Example 43)
Affinity DataIC50: 11nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate by Kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed