BDBM50341519 (S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl)benzoylamino)-5-(6-(methylamino)pyrazin-2-yl)-(1H)-pyridin-2-one::CHEMBL1765781

SMILES: CNc1cncc(n1)-c1c[nH]c(=O)c(NC(=O)c2ccc(cc2)N2CCC[C@H]2CN2CCCC2)c1

InChI Key: InChIKey=CMOPUHDFFUAOMA-UHFFFAOYSA-N

Data: 73 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 73 hits for monomerid = 50341519   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ITK/TSK (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Mast/stem cell growth factor receptor Kit (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Mast/stem cell growth factor receptor Kit (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK3 (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK2 (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase 7 (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		860	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 beta (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Serine/threonine-protein kinase Chk1 (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase HCK (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin-like growth factor 1 receptor (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Interleukin-1 receptor-associated kinase 4 (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 8 (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lyn (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1 (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 4 (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Insulin receptor (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Fyn (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ABL1 (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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RAC-alpha serine/threonine-protein kinase (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cytoplasmic tyrosine-protein kinase BMX (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase BTK (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Calcium/calmodulin-dependent protein kinase type 1D (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Calcium/calmodulin-dependent protein kinase type IV (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Ceramide kinase (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 8 (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase CSK (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Ephrin type-B receptor 2 (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C beta type (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Rho-associated protein kinase 2 (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 1 (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Inhibitor of nuclear factor kappa-B kinase subunit alpha (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Macrophage-stimulating protein receptor (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase Chk1 (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity mitogen-activated protein kinase kinase 6 (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Ribosomal protein S6 kinase alpha-5 (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase 3 (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase Nek1 (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 11 (Human)	BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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