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BDBM50341562 7-chloro-6-(4-chlorophenyl)-3-(3,5-dimethylphenyl)-4-(2-(piperidin-2-yl)ethoxy)-1,2-dihydroquinoline::CHEMBL1766109

SMILES: Cc1cc(C)cc(c1)C1=C(OCCC2CCCCN2)c2cc(c(Cl)cc2NC1)-c1ccc(Cl)cc1

InChI Key: InChIKey=YWHXYUQIWYAANP-UHFFFAOYSA-N

Data: 1 KI

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50341562   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50341562
PNG
(7-chloro-6-(4-chlorophenyl)-3-(3,5-dimethylphenyl)...)
Show SMILES Cc1cc(C)cc(c1)C1=C(OCCC2CCCCN2)c2cc(c(Cl)cc2NC1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C30H32Cl2N2O/c1-19-13-20(2)15-22(14-19)27-18-34-29-17-28(32)25(21-6-8-23(31)9-7-21)16-26(29)30(27)35-12-10-24-5-3-4-11-33-24/h6-9,13-17,24,33-34H,3-5,10-12,18H2,1-2H3
KEGG

UniProtKB/SwissProt

DrugBank
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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
0.0620n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of I125-somatostatin-14 from human SST2 expressed in CHO cells after 3 hrs by scintillation counting


J Med Chem 54: 2351-8 (2011)


Article DOI: 10.1021/jm101501b
BindingDB Entry DOI: 10.7270/Q2668DH8
More data for this
Ligand-Target Pair