BDBM50341579 CHEMBL1766104::{3-[7-Chloro-6-(1-methyl-1H-pyrazol-4-yl)-4-{2-[(2R)-piperidin-2-yl]ethoxy}quinolin-3-yl]phenyl}methanol

SMILES Cn1cc(cn1)-c1cc2c(OCC[C@H]3CCCCN3)c(cnc2cc1Cl)-c1cccc(CO)c1

InChI Key InChIKey=VQEDLQGAGVLAFF-OAQYLSRUSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50341579   

TargetSomatostatin receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50341579(CHEMBL1766104 | {3-[7-Chloro-6-(1-methyl-1H-pyrazo...)
Affinity DataKi:  0.130nMAssay Description:Displacement of I125-somatostatin-14 from human SST2 expressed in CHO cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50341579(CHEMBL1766104 | {3-[7-Chloro-6-(1-methyl-1H-pyrazo...)
Affinity DataIC50:  8.30nMAssay Description:Agonist activity at human SST2 expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP release after 40 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed