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BDBM50341644 CHEMBL1766540::N-(3-(4-Methylpiperazin-1-yl)-7-(trifluoromethyl)quinolin-5-yl)-3-nitrobenzenes ulfonamide

SMILES: CN1CCN(CC1)c1cnc2cc(cc(NS(=O)(=O)c3cccc(c3)[N+]([O-])=O)c2c1)C(F)(F)F

InChI Key: InChIKey=RPPZNCOJLMMRDV-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50341644   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50341644
PNG
(CHEMBL1766540 | N-(3-(4-Methylpiperazin-1-yl)-7-(t...)
Show SMILES CN1CCN(CC1)c1cnc2cc(cc(NS(=O)(=O)c3cccc(c3)[N+]([O-])=O)c2c1)C(F)(F)F
Show InChI InChI=1S/C21H20F3N5O4S/c1-27-5-7-28(8-6-27)16-12-18-19(25-13-16)9-14(21(22,23)24)10-20(18)26-34(32,33)17-4-2-3-15(11-17)29(30)31/h2-4,9-13,26H,5-8H2,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 99n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of purified recombinant c-Met after 60 mins by ELISA


J Med Chem 54: 2127-42 (2011)


Article DOI: 10.1021/jm101340q
BindingDB Entry DOI: 10.7270/Q2DR2VTS
More data for this
Ligand-Target Pair