BDBM50341733 3-amino-6-(4-(methylsulfonyl)phenyl)-N-phenylpyrazine-2-carboxamide::CHEMBL1766779::US10479784, Compound I-82::US10961232, Compound I-82

SMILES: CS(=O)(=O)c1ccc(cc1)-c1cnc(N)c(n1)C(=O)Nc1ccccc1

InChI Key: InChIKey=DUIHHZKTCSNTGM-UHFFFAOYSA-N

Data: 6 KI  4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50341733   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA-dependent protein kinase catalytic subunit (Human)	BDBM50341733 (3-amino-6-(4-(methylsulfonyl)phenyl)-N-phenylpyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase ATR (Human)	BDBM50341733 (3-amino-6-(4-(methylsulfonyl)phenyl)-N-phenylpyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
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Serine-protein kinase ATM (Human)	BDBM50341733 (3-amino-6-(4-(methylsulfonyl)phenyl)-N-phenylpyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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DNA-dependent protein kinase catalytic subunit (Human)	BDBM50341733 (3-amino-6-(4-(methylsulfonyl)phenyl)-N-phenylpyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase ATR (Human)	BDBM50341733 (3-amino-6-(4-(methylsulfonyl)phenyl)-N-phenylpyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase ATR (Human)	BDBM50341733 (3-amino-6-(4-(methylsulfonyl)phenyl)-N-phenylpyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Human)	BDBM50341733 (3-amino-6-(4-(methylsulfonyl)phenyl)-N-phenylpyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 1 (Human)	BDBM50341733 (3-amino-6-(4-(methylsulfonyl)phenyl)-N-phenylpyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 9 (Human)	BDBM50341733 (3-amino-6-(4-(methylsulfonyl)phenyl)-N-phenylpyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 12 (Human)	BDBM50341733 (3-amino-6-(4-(methylsulfonyl)phenyl)-N-phenylpyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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