BDBM50342229 2-(3-(6-Methylpyridin-2-yl)-4-(quinolin-6-yl)-1Hpyrazol-1-yl)-N-phenylethanethioamide::CHEMBL1766453

SMILES Cc1cccc(n1)-c1nn(CC(=S)Nc2ccccc2)cc1-c1ccc2ncccc2c1

InChI Key InChIKey=SCJCWFVWRBXJNG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50342229   

TargetTGF-beta receptor type-1(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50342229(2-(3-(6-Methylpyridin-2-yl)-4-(quinolin-6-yl)-1Hpy...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant p38alpha expressed in Escherichia coli using ATF2 as a substrate by radioisotopic protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50342229(2-(3-(6-Methylpyridin-2-yl)-4-(quinolin-6-yl)-1Hpy...)
Affinity DataIC50:  94nMAssay Description:Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed