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BDBM50343004 2-(4-amino-6-(4-methylpiperazin-1-yl)pyrimidin-2-ylamino)ethanol::CHEMBL1770989

SMILES: CN1CCN(CC1)c1cc(N)nc(NCCO)n1

InChI Key: InChIKey=ZUBSFEQQFUFJMC-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343004   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50343004
PNG
(2-(4-amino-6-(4-methylpiperazin-1-yl)pyrimidin-2-y...)
Show SMILES CN1CCN(CC1)c1cc(N)nc(NCCO)n1
Show InChI InChI=1S/C11H20N6O/c1-16-3-5-17(6-4-16)10-8-9(12)14-11(15-10)13-2-7-18/h8,18H,2-7H2,1H3,(H3,12,13,14,15)
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UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars

Article
PubMed
1.16E+3n/an/an/an/an/an/an/an/a



Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL


Assay Description
Displacement of [3H]histamine from human histamine H4 receptor


Bioorg Med Chem Lett 21: 3113-6 (2011)


Article DOI: 10.1016/j.bmcl.2011.03.017
BindingDB Entry DOI: 10.7270/Q24X5845
More data for this
Ligand-Target Pair