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BDBM50343008 (R)-6-(3-(methylamino)pyrrolidin-1-yl)-2-(pyrrolidin-1-yl)pyrimidin-4-amine::CHEMBL1770993

SMILES: CN[C@@H]1CCN(C1)c1cc(N)nc(n1)N1CCCC1

InChI Key: InChIKey=QKBCZNNMNSXGPE-SNVBAGLBSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343008   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine receptor (H4)


(Homo sapiens (human))
BDBM50343008
PNG
((R)-6-(3-(methylamino)pyrrolidin-1-yl)-2-(pyrrolid...)
Show SMILES CN[C@@H]1CCN(C1)c1cc(N)nc(n1)N1CCCC1
Show InChI InChI=1S/C13H22N6/c1-15-10-4-7-19(9-10)12-8-11(14)16-13(17-12)18-5-2-3-6-18/h8,10,15H,2-7,9H2,1H3,(H2,14,16,17)/t10-/m1/s1
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Similars

Article
PubMed
127n/an/an/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL


Assay Description
Displacement of [3H]histamine from human histamine H4 receptor


Bioorg Med Chem Lett 21: 3113-6 (2011)


Article DOI: 10.1016/j.bmcl.2011.03.017
BindingDB Entry DOI: 10.7270/Q24X5845
More data for this
Ligand-Target Pair