BindingDB logo
myBDB logout

BDBM50343011 (R)-2-(4-amino-6-(3-(methylamino)pyrrolidin-1-yl)pyrimidin-2-ylamino)ethanol::CHEMBL1770961

SMILES: CN[C@@H]1CCN(C1)c1cc(N)nc(NCCO)n1

InChI Key: InChIKey=YEONCWYNVXCPOF-MRVPVSSYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343011   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H4 receptor


(Homo sapiens (human))
BDBM50343011
PNG
((R)-2-(4-amino-6-(3-(methylamino)pyrrolidin-1-yl)p...)
Show SMILES CN[C@@H]1CCN(C1)c1cc(N)nc(NCCO)n1
Show InChI InChI=1S/C11H20N6O/c1-13-8-2-4-17(7-8)10-6-9(12)15-11(16-10)14-3-5-18/h6,8,13,18H,2-5,7H2,1H3,(H3,12,14,15,16)/t8-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
255n/an/an/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL


Assay Description
Displacement of [3H]histamine from human histamine H4 receptor


Bioorg Med Chem Lett 21: 3113-6 (2011)


Article DOI: 10.1016/j.bmcl.2011.03.017
BindingDB Entry DOI: 10.7270/Q24X5845
More data for this
Ligand-Target Pair