BDBM50343215 CHEMBL1615188::N-(6-(2-(methylthio)pyrimidin-4-yl)benzo[d]thiazol-2-yl)acetamide::N-{6-[2-(methylsulfanyl)pyrimidin-4-yl]-1,3-benzothiazol-2-yl}acetamide

SMILES CSc1nccc(n1)-c1ccc2nc(NC(C)=O)sc2c1

InChI Key InChIKey=UJBQBHAEDABZIB-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50343215   

LigandPNGBDBM50343215(N-(6-(2-(methylthio)pyrimidin-4-yl)benzo[d]thiazol...)
Affinity DataKi:  53nMAssay Description:Inhibition of human PI3Kalpha expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandPNGBDBM50343215(N-(6-(2-(methylthio)pyrimidin-4-yl)benzo[d]thiazol...)
Affinity DataKi:  53nMAssay Description:Inhibition of human PI3Kalpha expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50343215(N-(6-(2-(methylthio)pyrimidin-4-yl)benzo[d]thiazol...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of mTOR assessed as inhibition of 4EBP1 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50343215(N-(6-(2-(methylthio)pyrimidin-4-yl)benzo[d]thiazol...)
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of human mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed