BDBM50343327 CHEMBL1774235::cis-2-(((3R,4R)-4-(2-fluoro-4-(trifluoromethoxy)phenyl)-3-methylpiperidin-1-yl)methyl)-1-methyl-1H-imidazo[4,5-b]pyridine
SMILES C[C@H]1CN(Cc2nc3ncccc3n2C)CC[C@H]1c1ccc(OC(F)(F)F)cc1F
InChI Key InChIKey=CQTZXNPIJZSXKK-DZGCQCFKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50343327
Affinity DataKi: >4.68E+3nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation countingMore data for this Ligand-Target Pair
Affinity DataEC50: 31nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in HEK293 cells co-expressing Galpha15 G protein assessed as increase in glutamate-induced i...More data for this Ligand-Target Pair
Affinity DataEC50: 35nMAssay Description:Positive allosteric modulation of rat mGluR2 expressed in HEK293 cells co-expressing Galpha15 G protein assessed as increase in glutamate-induced int...More data for this Ligand-Target Pair