BDBM50343413 CHEMBL1201182::TEMSIROLIMUS::Torisel

SMILES: C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)OC(=O)C(C)(CO)CO)C)/C)O)OC)C)C)/C)OC

InChI Key: InChIKey=CBPNZQVSJQDFBE-UHFFFAOYSA-N

Data: 7 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50343413   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-binding cassette sub-family C member 4 (Human)	BDBM50343413 (Torisel | CHEMBL1201182 | TEMSIROLIMUS) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM50343413 (Torisel | CHEMBL1201182 | TEMSIROLIMUS) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 3 (Human)	BDBM50343413 (Torisel | CHEMBL1201182 | TEMSIROLIMUS) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 2 (Human)	BDBM50343413 (Torisel | CHEMBL1201182 | TEMSIROLIMUS) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.76E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase mTOR (Human)	BDBM50343413 (Torisel | CHEMBL1201182 | TEMSIROLIMUS) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase mTOR (Human)	BDBM50343413 (Torisel | CHEMBL1201182 | TEMSIROLIMUS) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase mTOR (Human)	BDBM50343413 (Torisel | CHEMBL1201182 | TEMSIROLIMUS) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase mTOR (Human)	BDBM50343413 (Torisel | CHEMBL1201182 | TEMSIROLIMUS) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair