BDBM50343505 (S)-4-(4-(4-fluorophenyl)-2-(isopropylsulfinyl)-1H-imidazol-5-yl)-N-isopropylpyridin-2-amine::CHEMBL1773499
SMILES CC(C)Nc1cc(ccn1)-c1nc([nH]c1-c1ccc(F)cc1)[S@@](=O)C(C)C
InChI Key InChIKey=LHMWWTJHYWIHMU-MHZLTWQESA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50343505
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen
Curated by ChEMBL
Eberhard-Karls-University Tu£Bingen
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen
Curated by ChEMBL
Eberhard-Karls-University Tu£Bingen
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as suppression of LPS-induced TNF-alpha release by immunosorbent non-radioactive enzyme as...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen
Curated by ChEMBL
Eberhard-Karls-University Tu£Bingen
Curated by ChEMBL
Affinity DataIC50: 610nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as suppression of LPS-induced TNF-alpha release by immunosorbent non-radioactive enzyme as...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen
Curated by ChEMBL
Eberhard-Karls-University Tu£Bingen
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair