BDBM50343674 4-(4-(piperazin-1-ylsulfonyl)phenyl)-N-(piperidin-4-yl)pyrimidin-2-amine::CHEMBL1773334

SMILES: O=S(=O)(N1CCNCC1)c1ccc(cc1)-c1ccnc(NC2CCNCC2)n1

InChI Key: InChIKey=IXMFEZPRVSMTLE-UHFFFAOYSA-N

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50343674   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inhibitor of nuclear factor kappa-B kinase subunit alpha (Human)	BDBM50343674 (4-(4-(piperazin-1-ylsulfonyl)phenyl)-N-(piperidin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 8 (Human)	BDBM50343674 (4-(4-(piperazin-1-ylsulfonyl)phenyl)-N-(piperidin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.97E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 9 (Human)	BDBM50343674 (4-(4-(piperazin-1-ylsulfonyl)phenyl)-N-(piperidin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Human)	BDBM50343674 (4-(4-(piperazin-1-ylsulfonyl)phenyl)-N-(piperidin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Inhibitor of nuclear factor kappa-B kinase subunit beta (Human)	BDBM50343674 (4-(4-(piperazin-1-ylsulfonyl)phenyl)-N-(piperidin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM50343674 (4-(4-(piperazin-1-ylsulfonyl)phenyl)-N-(piperidin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 11 (Human)	BDBM50343674 (4-(4-(piperazin-1-ylsulfonyl)phenyl)-N-(piperidin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair