BDBM50344105 2-((R)-4-methyl-3-oxo-1-tosylpiperazin-2-yl)-N-((R)-6-(piperidin-1-ylmethyl)-1,2,3,4-tetrahydronaphthalen-1-yl)acetamide::CHEMBL1777963

SMILES CN1CCN([C@H](CC(=O)N[C@@H]2CCCc3cc(CN4CCCCC4)ccc23)C1=O)S(=O)(=O)c1ccc(C)cc1

InChI Key InChIKey=YUCYSNBRNZOMJX-VSGBNLITSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344105   

TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50344105(2-((R)-4-methyl-3-oxo-1-tosylpiperazin-2-yl)-N-((R...)
Affinity DataKi:  442nMAssay Description:Antagonist activity at human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50344105(2-((R)-4-methyl-3-oxo-1-tosylpiperazin-2-yl)-N-((R...)
Affinity DataIC50:  98.6nMAssay Description:Antagonist activity at human bradykinin B1 receptor expressed in CHO cells assessed as inhibition of agonist-induced calcium efflux by aquerin based ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed