BDBM50344366 1-(2-chloro-5-(trifluoromethyl)phenyl)-3-(7-hydroxynaphthalen-1-yl)urea::CHEMBL1779686

SMILES Oc1ccc2cccc(NC(=O)Nc3cc(ccc3Cl)C(F)(F)F)c2c1

InChI Key InChIKey=RIOIOAYAPNNFPT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344366   

TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Bayer Yakuhin

Curated by ChEMBL
LigandPNGBDBM50344366(1-(2-chloro-5-(trifluoromethyl)phenyl)-3-(7-hydrox...)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at rat TRPV1 expressed in CHO cells co-expressing aequorin and CRE-luciferase reporter gene assessed as inhibition of capsaicin-i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Bayer Yakuhin

Curated by ChEMBL
LigandPNGBDBM50344366(1-(2-chloro-5-(trifluoromethyl)phenyl)-3-(7-hydrox...)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells co-expressing aequorin and CRE-luciferase reporter gene assessed as inhibition of capsaicin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed