BDBM50344383 6-methyl-2-(thiophen-2-ylethynyl)-7,8-dihydro-1,6-naphthyridin-5(6H)-one::CHEMBL1779857
SMILES CN1CCc2nc(ccc2C1=O)C#Cc1cccs1
InChI Key InChIKey=AJDOCVSDQVAAMU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50344383
Affinity DataKi: 2.17E+3nMAssay Description:Displacement of [3H]-MPEP from human mGluR5 expressed in HEK293 cells after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 451nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as inhibition of L-glutamate-induced calcium mobilization by FLIPR ...More data for this Ligand-Target Pair