BDBM50344637 CHEMBL1779078::N'-(1-methyl-2-oxoindolin-3-ylidene)-4-nitrobenzohydrazide

SMILES: CN1C(=O)C(=NNC(=O)c2ccc(cc2)[N+]([O-])=O)c2ccccc12

InChI Key: InChIKey=MYTZOUJVRPGAPY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344637   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50344637 (CHEMBL1779078 | N'-(1-methyl-2-oxoindolin-3-yliden...) Show SMILES CN1C(=O)C(=NNC(=O)c2ccc(cc2)[N+]([O-])=O)c2ccccc12 Show InChI InChI=1S/C16H12N4O4/c1-19-13-5-3-2-4-12(13)14(16(19)22)17-18-15(21)10-6-8-11(9-7-10)20(23)24/h2-9H,1H3,(H,18,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of purified c-Met using poly(glu,tyr) as substrate after 60 mins by ELISA				Bioorg Med Chem Lett 21: 3749-54 (2011) Article DOI: 10.1016/j.bmcl.2011.04.064 BindingDB Entry DOI: 10.7270/Q2V1254B
					More data for this Ligand-Target Pair