BindingDB PrimarySearch

BDBM50344942 CHEMBL532::E-MYCIN E::ERYTHROMYCIN::ERYTHROMYCIN ETHYLSUCCINATE::Erycette::Erymax::Erythromycin A::Erythromycin C::Ilotycin::T-Stat::US20240118263, Compound Erythromycin

SMILES: CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O

InChI Key: InChIKey=ULGZDMOVFRHVEP-UHFFFAOYSA-N

Data: 6 KI 32 IC50 2 Kd 9 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 49 hits for monomerid = 50344942
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Motilin receptor (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	50.1	n/a	n/a	n/a	n/a
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Low molecular weight phosphotyrosine protein phosphatase (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4.71E+4	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Mouse)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Motilin receptor (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Lanosterol 14-alpha demethylase (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Mouse)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Motilin receptor (Rabbit)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
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Motilin receptor (Rabbit)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
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Motilin receptor (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
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Albumin (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a
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Motilin receptor (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	71	n/a	n/a	n/a	n/a	2.5	n/a
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Motilin receptor (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
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Multidrug and toxin extrusion protein 1 (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Chitinase B (Serratia marcescens)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2J2 (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 4 (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	6.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Low molecular weight phosphotyrosine protein phosphatase (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Selenoprotein H (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	1.04E+4	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 4 (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 2 (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 3 (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 2 (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 3 (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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TBA				More data for this Ligand-Target Pair
Motilin receptor (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
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Cytochrome P450 1B1 (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Co-chaperonin GroES (Escherichia coli)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Thiosulfate sulfurtransferase (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Co-chaperonin GroES (Escherichia coli)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.78E+5	n/a	n/a	n/a	n/a	n/a	n/a
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60 kDa heat shock protein, mitochondrial (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Chaperonin GroEL (Escherichia coli)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Motilin receptor (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	50.1	n/a	n/a	n/a	n/a
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TBA				More data for this Ligand-Target Pair
Motilin receptor (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	631	n/a	n/a	n/a	n/a
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Motilin receptor (Rabbit)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
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Motilin receptor (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	3.78E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier organic anion transporter family member (Zebrafish)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	8.82E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Mouse)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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TBA				More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Mouse)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Human)	BDBM50344942 (CHEMBL532 \| ERYTHROMYCIN \| Erycette \| Erymax \| Ery...) Show SMILES Show InChI	GoogleScholar	UniChem	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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