BDBM50345244 5-(6-(piperidin-4-ylamino)pyrazin-2-yl)benzofuran-2-carboxylic acid::CHEMBL1782515

SMILES OC(=O)c1cc2cc(ccc2o1)-c1cncc(NC2CCNCC2)n1

InChI Key InChIKey=PWLTUXUDBOARFK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50345244   

TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50345244(5-(6-(piperidin-4-ylamino)pyrazin-2-yl)benzofuran-...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human Pim2 using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 90 mins by off-chip mobility shift methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50345244(5-(6-(piperidin-4-ylamino)pyrazin-2-yl)benzofuran-...)
Affinity DataIC50:  210nMAssay Description:Inhibition of human Pim1 using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 45 mins by off-chip mobility shift methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed