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BDBM50345487 CHEMBL1784895::Uridine-5'-(4-chlorophenyl)-tetraphosphate

SMILES: O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)Oc1ccc(Cl)cc1)n1ccc(=O)[nH]c1=O

InChI Key: InChIKey=MXJPKELDUVHDEF-RVUVTHLHNA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50345487   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Purinergic receptor P2Y2


(Homo sapiens (Human))
BDBM50345487
PNG
(CHEMBL1784895 | Uridine-5'-(4-chlorophenyl)-tetrap...)
Show SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)Oc1ccc(Cl)cc1)n1ccc(=O)[nH]c1=O
Show InChI InChI=1/C15H19ClN2O18P4/c16-8-1-3-9(4-2-8)33-38(25,26)35-40(29,30)36-39(27,28)34-37(23,24)31-7-10-12(20)13(21)14(32-10)18-6-5-11(19)17-15(18)22/h1-6,10,12-14,20-21H,7H2,(H,23,24)(H,25,26)(H,27,28)(H,29,30)(H,17,19,22)/t10-,12-,13-,14-/s2
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PC sid
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Similars

Article
PubMed
n/an/an/an/a 6.60E+3n/an/an/an/a



NIDDK

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production after 30 mins by sc...


J Med Chem 54: 4018-33 (2011)


Article DOI: 10.1021/jm101591j
BindingDB Entry DOI: 10.7270/Q22F7NT0
More data for this
Ligand-Target Pair