BDBM50345529 CHEMBL1784354::N-(1-(4-(4-fluorophenyl)piperazin-1-ylsulfonyl)-2-methylpropan-2-yl)-N-hydroxyformamide
SMILES CC(C)(CS(=O)(=O)N1CCN(CC1)c1ccc(F)cc1)N(O)C=O
InChI Key InChIKey=JKTGELXOMXEKJI-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50345529
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant human MMP-14 assessed as substrate cleavage after 20 hrs by fluorescence assayMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 92nMAssay Description:Inhibition of ADAMTS-4 assessed as substrate cleavage after 16 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human MMP-1 assessed as substrate cleavage after 20 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant human MMP-13 assessed as substrate cleavage after 20 hrs by fluorescence assayMore data for this Ligand-Target Pair