BDBM50345740 3-(6-ethoxynaphthalen-2-yl)-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine::CHEMBL1785021::CHEMBL2070048::US10544104, Compound 7r::US11247972, Compound 7r::US9765037, Compound 7r

SMILES: CCOc1ccc2cc(ccc2c1)-c1nn(C(C)C)c2ncnc(N)c12

InChI Key: InChIKey=MJOCJDMQRCJQJF-UHFFFAOYSA-N

Data: 2 KI  25 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 27 hits for monomerid = 50345740   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ABL1 (Human)	BDBM50345740 (CHEMBL1785021 | CHEMBL2070048 | 3-(6-ethoxynaphtha...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM50345740 (CHEMBL1785021 | CHEMBL2070048 | 3-(6-ethoxynaphtha...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ABL1 (Human)	BDBM50345740 (CHEMBL1785021 | CHEMBL2070048 | 3-(6-ethoxynaphtha...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase CSK (Human)	BDBM50345740 (CHEMBL1785021 | CHEMBL2070048 | 3-(6-ethoxynaphtha...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Ephrin type-A receptor 3 (Human)	BDBM50345740 (CHEMBL1785021 | CHEMBL2070048 | 3-(6-ethoxynaphtha...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM50345740 (CHEMBL1785021 | CHEMBL2070048 | 3-(6-ethoxynaphtha...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM50345740 (CHEMBL1785021 | CHEMBL2070048 | 3-(6-ethoxynaphtha...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50345740 (CHEMBL1785021 | CHEMBL2070048 | 3-(6-ethoxynaphtha...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
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Calmodulin-domain protein kinase 1 (Toxoplasma gondii)	BDBM50345740 (CHEMBL1785021 | CHEMBL2070048 | 3-(6-ethoxynaphtha...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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Calcium/calmodulin dependent protein kinase with a kinas domain and 4 calmodulin-like EF hands (Cryptosporidium parvum (strain Iowa II))	BDBM50345740 (CHEMBL1785021 | CHEMBL2070048 | 3-(6-ethoxynaphtha...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
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cGMP-dependent protein kinase (Toxoplasma gondii)	BDBM50345740 (CHEMBL1785021 | CHEMBL2070048 | 3-(6-ethoxynaphtha...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50345740 (CHEMBL1785021 | CHEMBL2070048 | 3-(6-ethoxynaphtha...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Calmodulin-domain protein kinase 1 (Toxoplasma gondii)	BDBM50345740 (CHEMBL1785021 | CHEMBL2070048 | 3-(6-ethoxynaphtha...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Toxoplasma gondii)	BDBM50345740 (CHEMBL1785021 | CHEMBL2070048 | 3-(6-ethoxynaphtha...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Calcium/calmodulin dependent protein kinase with a kinas domain and 4 calmodulin-like EF hands (Cryptosporidium parvum (strain Iowa II))	BDBM50345740 (CHEMBL1785021 | CHEMBL2070048 | 3-(6-ethoxynaphtha...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase HCK (Human)	BDBM50345740 (CHEMBL1785021 | CHEMBL2070048 | 3-(6-ethoxynaphtha...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	218	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ABL1 (Human)	BDBM50345740 (CHEMBL1785021 | CHEMBL2070048 | 3-(6-ethoxynaphtha...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50345740 (CHEMBL1785021 | CHEMBL2070048 | 3-(6-ethoxynaphtha...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	549	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50345740 (CHEMBL1785021 | CHEMBL2070048 | 3-(6-ethoxynaphtha...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
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Calmodulin-domain protein kinase 1, putative (Cryptosporidium parvum (strain Iowa II))	BDBM50345740 (CHEMBL1785021 | CHEMBL2070048 | 3-(6-ethoxynaphtha...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Calmodulin-domain protein kinase 1 (Toxoplasma gondii)	BDBM50345740 (CHEMBL1785021 | CHEMBL2070048 | 3-(6-ethoxynaphtha...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Tyrosine-protein kinase HCK (Human)	BDBM50345740 (CHEMBL1785021 | CHEMBL2070048 | 3-(6-ethoxynaphtha...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	218	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM50345740 (CHEMBL1785021 | CHEMBL2070048 | 3-(6-ethoxynaphtha...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50345740 (CHEMBL1785021 | CHEMBL2070048 | 3-(6-ethoxynaphtha...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Calcium-dependent protein kinase 1 (Cryptosporidium parvum)	BDBM50345740 (CHEMBL1785021 | CHEMBL2070048 | 3-(6-ethoxynaphtha...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50345740 (CHEMBL1785021 | CHEMBL2070048 | 3-(6-ethoxynaphtha...) Show SMILES Show InChI	GoogleScholar	UniChem		200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM50345740 (CHEMBL1785021 | CHEMBL2070048 | 3-(6-ethoxynaphtha...) Show SMILES Show InChI	GoogleScholar	UniChem		1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair