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BDBM50345891 CHEMBL1783708::tert-butyl 4-(3-((3-amino-6-propylpyrazin-2-yl)methyl)thioureido)phenylcarbamate

SMILES: CCCc1cnc(N)c(CNC(=S)Nc2ccc(NC(=O)OC(C)(C)C)cc2)n1

InChI Key: InChIKey=TVGLRNNXRUFLFX-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50345891   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
MAP kinase-activated protein kinase 2


(Homo sapiens (Human))
BDBM50345891
PNG
(CHEMBL1783708 | tert-butyl 4-(3-((3-amino-6-propyl...)
Show SMILES CCCc1cnc(N)c(CNC(=S)Nc2ccc(NC(=O)OC(C)(C)C)cc2)n1
Show InChI InChI=1S/C20H28N6O2S/c1-5-6-15-11-22-17(21)16(24-15)12-23-18(29)25-13-7-9-14(10-8-13)26-19(27)28-20(2,3)4/h7-11H,5-6,12H2,1-4H3,(H2,21,22)(H,26,27)(H2,23,25,29)
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 45n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrate


Bioorg Med Chem Lett 19: 3238-42 (2009)


Article DOI: 10.1016/j.bmcl.2009.04.088
BindingDB Entry DOI: 10.7270/Q2QZ2B88
More data for this
Ligand-Target Pair