BDBM50345948 9-Prop-2-ynylamino-3-p-tolyl-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one::CHEMBL1783875

SMILES Cc1ccc(cc1)-n1cnc2c(sc3nccc(NCC#C)c23)c1=O

InChI Key InChIKey=CEJVVRHTVXTMIG-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50345948   

TargetMetabotropic glutamate receptor 1(RAT)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345948(9-Prop-2-ynylamino-3-p-tolyl-3H-pyrido[3',2':4,5]t...)
Affinity DataKi:  1.60nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345948(9-Prop-2-ynylamino-3-p-tolyl-3H-pyrido[3',2':4,5]t...)
Affinity DataIC50:  1.5nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345948(9-Prop-2-ynylamino-3-p-tolyl-3H-pyrido[3',2':4,5]t...)
Affinity DataIC50: >3.00E+3nMAssay Description:Antagonist activity at human mGluR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed