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BDBM50346263 2-(3-(4-chlorobenzyl)-2-imino-2,3-dihydro-1H-benzo[d]imidazol-1-yl)ethanol::CHEMBL1616222

SMILES: OCCn1c2ccccc2n(Cc2ccc(Cl)cc2)c1=N

InChI Key: InChIKey=BDBJVOWIFIUXCB-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50346263   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium/glucose cotransporter 2


(Homo sapiens (Human))
BDBM50346263
PNG
(2-(3-(4-chlorobenzyl)-2-imino-2,3-dihydro-1H-benzo...)
Show SMILES OCCn1c2ccccc2n(Cc2ccc(Cl)cc2)c1=N
Show InChI InChI=1S/C16H16ClN3O/c17-13-7-5-12(6-8-13)11-20-15-4-2-1-3-14(15)19(9-10-21)16(20)18/h1-8,18,21H,9-11H2
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Similars

Article
PubMed
n/an/an/an/a 3.11E+4n/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]-alpha-methylglucopyranoside uptake after 2 hrs by liquid scintilla...


J Med Chem 53: 8770-4 (2010)


Article DOI: 10.1021/jm101080v
BindingDB Entry DOI: 10.7270/Q2N29X9T
More data for this
Ligand-Target Pair