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BDBM50346528 2,5-dihydro-1H-pyrrole-2-carboximidamide::CHEMBL1783093

SMILES: NC(=N)C1=NCCC1

InChI Key: InChIKey=IAQUICGFTDBDIC-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50346528   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nitric oxide synthase, inducible


(Homo sapiens (Human))
BDBM50346528
PNG
(2,5-dihydro-1H-pyrrole-2-carboximidamide | CHEMBL1...)
Show SMILES NC(=N)C1=NCCC1
Show InChI InChI=1S/C5H9N3/c6-5(7)4-2-1-3-8-4/h1-3H2,(H3,6,7)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 180n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of human recombinant iNOS by microtiter plate assay


Bioorg Med Chem Lett 21: 3037-40 (2011)


Article DOI: 10.1016/j.bmcl.2011.03.038
BindingDB Entry DOI: 10.7270/Q2FB538T
More data for this
Ligand-Target Pair