BDBM50347567 CHEMBL1801712

SMILES CCc1nc2c(C)cc(C)nc2n1[C@H]1CCc2cc(ccc12)-c1ccccc1-c1nnn[nH]1

InChI Key InChIKey=PACFDFGGIPMOKL-QFIPXVFZSA-N

Data  1 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50347567   

TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50347567(CHEMBL1801712)Copy SMILESCopy InChI

Affinity DataEC50:  591nMAssay Description:Partial agonist activity at human PPARgamma-LBD/Gal4 DNA binding domain by transactivation assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50347567(CHEMBL1801712)Copy SMILESCopy InChI

Affinity DataIC50:  7.60nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after 60 mins by scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI