BDBM50348452 AZD-8055::CHEMBL1801204::US9102670, 1a

SMILES: COc1ccc(cc1CO)-c1ccc2c(nc(nc2n1)N1CCOC[C@@H]1C)N1CCOC[C@@H]1C

InChI Key: InChIKey=KVLFRAWTRWDEDF-UHFFFAOYSA-N

Data: 16 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50348452   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Human)	BDBM50348452 (CHEMBL1801204 | US9102670, 1a | AZD-8055) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM50348452 (CHEMBL1801204 | US9102670, 1a | AZD-8055) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM50348452 (CHEMBL1801204 | US9102670, 1a | AZD-8055) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50348452 (CHEMBL1801204 | US9102670, 1a | AZD-8055) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM50348452 (CHEMBL1801204 | US9102670, 1a | AZD-8055) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM50348452 (CHEMBL1801204 | US9102670, 1a | AZD-8055) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM50348452 (CHEMBL1801204 | US9102670, 1a | AZD-8055) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM50348452 (CHEMBL1801204 | US9102670, 1a | AZD-8055) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM50348452 (CHEMBL1801204 | US9102670, 1a | AZD-8055) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM50348452 (CHEMBL1801204 | US9102670, 1a | AZD-8055) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM50348452 (CHEMBL1801204 | US9102670, 1a | AZD-8055) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM50348452 (CHEMBL1801204 | US9102670, 1a | AZD-8055) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM50348452 (CHEMBL1801204 | US9102670, 1a | AZD-8055) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Target of rapamycin complex subunit LST8 (Human)	BDBM50348452 (CHEMBL1801204 | US9102670, 1a | AZD-8055) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Target of rapamycin complex 2 subunit MAPKAP1 (Human)	BDBM50348452 (CHEMBL1801204 | US9102670, 1a | AZD-8055) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM50348452 (CHEMBL1801204 | US9102670, 1a | AZD-8055) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM50348452 (CHEMBL1801204 | US9102670, 1a | AZD-8055) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Ferrochelatase, mitochondrial [R115L] (Human)	BDBM50348452 (CHEMBL1801204 | US9102670, 1a | AZD-8055) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair