BDBM50348843 CHEMBL1806767

SMILES: Cn1c(OCCOc2ccc(Cl)cc2)nc2n(C)c(=O)n(C)c(=O)c12

InChI Key: InChIKey=XPLFQPMQLCSNFG-UHFFFAOYSA-N

Data: 2 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50348843   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50348843 (CHEMBL1806767) Show SMILES Cn1c(OCCOc2ccc(Cl)cc2)nc2n(C)c(=O)n(C)c(=O)c12 Show InChI InChI=1S/C16H17ClN4O4/c1-19-12-13(20(2)16(23)21(3)14(12)22)18-15(19)25-9-8-24-11-6-4-10(17)5-7-11/h4-7H,8-9H2,1-3H3	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
North-West University Curated by ChEMBL					Assay Description Inhibition of recombinant human MAOB expressed in baculovirus infected insect cell microsomes using kynuramine as substrate assessed as formation of ...				Eur J Med Chem 46: 3474-85 (2011) Article DOI: 10.1016/j.ejmech.2011.05.014 BindingDB Entry DOI: 10.7270/Q2JH3MJH
					More data for this Ligand-Target Pair
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM50348843 (CHEMBL1806767) Show SMILES Cn1c(OCCOc2ccc(Cl)cc2)nc2n(C)c(=O)n(C)c(=O)c12 Show InChI InChI=1S/C16H17ClN4O4/c1-19-12-13(20(2)16(23)21(3)14(12)22)18-15(19)25-9-8-24-11-6-4-10(17)5-7-11/h4-7H,8-9H2,1-3H3	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	640	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
North-West University Curated by ChEMBL					Assay Description Inhibition of recombinant human MAOA expressed in baculovirus infected insect cell microsomes using kynuramine as substrate assessed as formation of ...				Eur J Med Chem 46: 3474-85 (2011) Article DOI: 10.1016/j.ejmech.2011.05.014 BindingDB Entry DOI: 10.7270/Q2JH3MJH
					More data for this Ligand-Target Pair
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM50348843 (CHEMBL1806767) Show SMILES Cn1c(OCCOc2ccc(Cl)cc2)nc2n(C)c(=O)n(C)c(=O)c12 Show InChI InChI=1S/C16H17ClN4O4/c1-19-12-13(20(2)16(23)21(3)14(12)22)18-15(19)25-9-8-24-11-6-4-10(17)5-7-11/h4-7H,8-9H2,1-3H3	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
North-West University Curated by ChEMBL					Assay Description Inhibition of recombinant human MAOA expressed in baculovirus infected insect cell microsomes using kynuramine as substrate assessed as formation of ...				Eur J Med Chem 46: 3474-85 (2011) Article DOI: 10.1016/j.ejmech.2011.05.014 BindingDB Entry DOI: 10.7270/Q2JH3MJH
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50348843 (CHEMBL1806767) Show SMILES Cn1c(OCCOc2ccc(Cl)cc2)nc2n(C)c(=O)n(C)c(=O)c12 Show InChI InChI=1S/C16H17ClN4O4/c1-19-12-13(20(2)16(23)21(3)14(12)22)18-15(19)25-9-8-24-11-6-4-10(17)5-7-11/h4-7H,8-9H2,1-3H3	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	183	n/a	n/a	n/a	n/a	n/a	n/a
North-West University Curated by ChEMBL					Assay Description Inhibition of recombinant human MAOB expressed in baculovirus infected insect cell microsomes using kynuramine as substrate assessed as formation of ...				Eur J Med Chem 46: 3474-85 (2011) Article DOI: 10.1016/j.ejmech.2011.05.014 BindingDB Entry DOI: 10.7270/Q2JH3MJH
					More data for this Ligand-Target Pair