BDBM50349265 CHEMBL1807228
SMILES COc1cccc(c1)-c1ncccc1NC(=O)N1CCn2c(C1)c(O)n([C@H]1C[C@@H]1c1ccccc1)c2=O
InChI Key InChIKey=PGARAOQBRAKKPD-GGAORHGYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50349265
Affinity DataIC50: 82nMAssay Description:Antagonist activity at smoothened expressed in mouse Shh Light2 cells co-expressing Gli-dependent reporter gene assessed as inhibition of Hh pathwayMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Displacement of [125I]-PA cyclopamine from smoothened expressed in african green monkey COS-1 cells after 10 mins by autoradiographyMore data for this Ligand-Target Pair