BDBM50350511 CHEMBL1814816

SMILES CC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCCC(N)=O)NC(=O)[C@H](CCCCNC(C)=O)NC(C)=O)C(N)=O

InChI Key InChIKey=LDEKRXSQAZNKHV-FKBYEOEOSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50350511   

TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Akron

Curated by ChEMBL
LigandPNGBDBM50350511(CHEMBL1814816)
Affinity DataIC50:  2.90E+5nMAssay Description:Inhibition of human GST-tagged SIRT1 using H2NHK-AcK-LM-COOH as substrate assessed as enzymatic deacetylation product formation after 5 mins by HPLC ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
University Of Akron

Curated by ChEMBL
LigandPNGBDBM50350511(CHEMBL1814816)
Affinity DataIC50:  2.14E+5nMAssay Description:Inhibition of human SIRT3 (102-399) using H2N-KRLPKTRSG-AcK-VMRRLLRKII-COOH as substrate assessed as enzymatic deacetylation product formation after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Akron

Curated by ChEMBL
LigandPNGBDBM50350511(CHEMBL1814816)
Affinity DataIC50:  1.90E+5nMAssay Description:Inhibition of human full length SIRT2 using H2N-MPSD-AcK-TIGG-COOH as substrate assessed as enzymatic deacetylation product formation after 60 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed