BDBM50350947 CHEMBL1818218

SMILES CC(C)CNc1nc(ncc1C(=O)NCc1ccccc1)N1CCN(CC2CCCOC2)CC1

InChI Key InChIKey=PPANZCQXFYBGHN-UHFFFAOYSA-N

Data  1 IC50  2 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50350947   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50350947(CHEMBL1818218)Copy SMILESCopy InChI

Affinity DataEC50:  23nMAssay Description:Agonist activity at human TRPA1 channel expressed in HEK293 cells assessed as calcium influx measured at every 1 second for 60 seconds by fluorescenc...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLMCE
PC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
Pfizer

Curated by ChEMBL

LigandBDBM50350947(CHEMBL1818218)Copy SMILESCopy InChI

Affinity DataEC50:  97nMAssay Description:Agonist activity at rat TRPA1 channel expressed in HEK293 cells assessed as calcium influx measured at every 1 second for 60 seconds by fluorescence ...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLMCE
PC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50350947(CHEMBL1818218)Copy SMILESCopy InChI

Affinity DataIC50:  580nMAssay Description:Inhibition of human ERG expressed in human HEK293 cells by patch-clamp electrophysiologyMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLMCE
PC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI