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BDBM50351521 CHEMBL1824658

SMILES: CCc1cc(ccn1)-c1nc(cs1)-c1ccc(C)cc1

InChI Key: InChIKey=WAUMGXOXXFKMTR-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50351521   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sterol regulatory element-binding protein 2


(Homo sapiens (Human))
BDBM50351521
PNG
(CHEMBL1824658)
Show SMILES CCc1cc(ccn1)-c1nc(cs1)-c1ccc(C)cc1
Show InChI InChI=1S/C17H16N2S/c1-3-15-10-14(8-9-18-15)17-19-16(11-20-17)13-6-4-12(2)5-7-13/h4-11H,3H2,1-2H3
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 6.80E+3n/an/an/an/an/an/a



Kyoto University

Curated by ChEMBL


Assay Description
Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...


J Med Chem 54: 4923-7 (2011)


Article DOI: 10.1021/jm200304y
BindingDB Entry DOI: 10.7270/Q2NG4R0Z
More data for this
Ligand-Target Pair