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BDBM50351638 CHEMBL1823124

SMILES: Cn1cnc(c1)-c1cc2cccc(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4)cc3F)c2s1

InChI Key: InChIKey=LBHAQQVFFSPETP-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50351638   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50351638
PNG
(CHEMBL1823124)
Show SMILES Cn1cnc(c1)-c1cc2cccc(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4)cc3F)c2s1
Show InChI InChI=1S/C27H21FN4O2S2/c1-32-15-21(29-16-32)24-13-18-8-5-9-23(26(18)36-24)34-22-11-10-19(14-20(22)28)30-27(35)31-25(33)12-17-6-3-2-4-7-17/h2-11,13-16H,12H2,1H3,(H2,30,31,33,35)
PDB
MMDB

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Similars

Article
PubMed
n/an/a 29n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of human c-MET


Eur J Med Chem 46: 3675-80 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.031
BindingDB Entry DOI: 10.7270/Q2891676
More data for this
Ligand-Target Pair