BDBM50351759 CHEMBL1823493

SMILES O[C@H]1C[C@@H](O[C@@H]1COP([O-])([O-])=O)n1cc(C=CC#N)c(=O)[nH]c1=O

InChI Key InChIKey=BOBJSVJSCXBKSH-IVZWLZJFSA-L

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50351759   

TargetThymidylate synthase ThyA(Mycobacterium tuberculosis)
Katholieke Universiteit Leuven

Curated by ChEMBL
LigandPNGBDBM50351759(CHEMBL1823493)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis His-tagged ThyA-mediated dTMP synthesis expressed in BL21 (DE3) Escherichia coli RbCl cells after 30 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlavin-dependent thymidylate synthase(Mycobacterium tuberculosis)
Katholieke Universiteit Leuven

Curated by ChEMBL
LigandPNGBDBM50351759(CHEMBL1823493)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis ThyX-mediated dTMP synthesis using [5-3H]dUMP as substrate after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed