BDBM50352556 CHEMBL1825133

SMILES CC(Oc1cc(cnc1N)-c1cnn(CC2CN(CC(N)=O)C2)c1)c1c(Cl)ccc(F)c1Cl

InChI Key InChIKey=ZLWXGIXHQBMQNJ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50352556   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50352556(CHEMBL1825133)
Affinity DataKi:  24nMAssay Description:Binding affinity to human recombinant c-MET assessed as inhibition of autophosphorylation by continuous fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50352556(CHEMBL1825133)
Affinity DataIC50:  53nMAssay Description:Inhibition of human recombinant c-MET kinase expressed in A549 cells assessed as inhibition of HGF-induced autophosphorylation by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed