BDBM50352850 CHEMBL1824335
SMILES CCn1cc(cn1)[C@]1(N=C(N)N(C)C1=O)c1cccc(c1)-c1cccnc1F
InChI Key InChIKey=IKJXVRPWMOVIMY-HXUWFJFHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50352850
Affinity DataIC50: 450nMAssay Description:Inhibition of BACE2 by FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 490nMAssay Description:Inhibition of BACE1 expressed in CHO cells expressing wild type human APP assessed as inhibition of amyloid beta-40 or 42 production by ELISA assayMore data for this Ligand-Target Pair
Affinity DataEC50: >2.50E+3nMAssay Description:Inhibition of BACE1 expressed in CHO cells expressing wild type human APP assessed as inhibition of amyloid beta-40 or 42 production by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of cathepsin D by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.39E+3nMAssay Description:Inhibition of BACE2 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.96E+3nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair