BDBM50352854 CHEMBL1824361

SMILES CCC(=O)c1cc(cs1)[C@@]1(N=C(N)N(C)C1=O)c1cccc(c1)-c1cccnc1F

InChI Key InChIKey=SYHWIMVHWVXBDN-QFIPXVFZSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50352854   

TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50352854(CHEMBL1824361)
Affinity DataIC50:  10nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50352854(CHEMBL1824361)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of cathepsin D by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50352854(CHEMBL1824361)
Affinity DataIC50:  50nMAssay Description:Inhibition of BACE2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50352854(CHEMBL1824361)
Affinity DataEC50:  10nMAssay Description:Inhibition of BACE1 expressed in CHO cells expressing wild type human APP assessed as inhibition of amyloid beta-40 or 42 production by ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed