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BDBM50353096 CHEMBL1829131

SMILES: COc1ccc(cc1)C(=O)Nc1cc(ccc1OCCCN1CCN(Cc2ccc(OC)c(OC)c2OC)CC1)C(=O)NC(N)=N

InChI Key: InChIKey=FPQJAKQEXYFLBN-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50353096   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium/hydrogen exchanger 1


(Rattus norvegicus)
BDBM50353096
PNG
(CHEMBL1829131)
Show SMILES COc1ccc(cc1)C(=O)Nc1cc(ccc1OCCCN1CCN(Cc2ccc(OC)c(OC)c2OC)CC1)C(=O)NC(N)=N
Show InChI InChI=1S/C33H42N6O7/c1-42-25-10-6-22(7-11-25)31(40)36-26-20-23(32(41)37-33(34)35)8-12-27(26)46-19-5-14-38-15-17-39(18-16-38)21-24-9-13-28(43-2)30(45-4)29(24)44-3/h6-13,20H,5,14-19,21H2,1-4H3,(H,36,40)(H4,34,35,37,41)
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Similars

Article
PubMed
n/an/a 225n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysis


Eur J Med Chem 46: 4107-16 (2011)


Article DOI: 10.1016/j.ejmech.2011.06.011
BindingDB Entry DOI: 10.7270/Q27081T0
More data for this
Ligand-Target Pair